A pair of enantiotropic carbazole alkaloids from the stems of <i>Clausena emarginata</i> C. C. Huang

Two new carbazole alkaloids clauemarazole H (<b>1</b>) and clauemarazole I (<b>2</b>) were isolated from the stems of <i>Clausena emarginata</i> C. C. Huang. Their structures were confirmed by comprehensive spectroscopic analyses, and the absolute configurations were determined based on ECD experiments. The two compounds were evaluated for their neuroprotective effects against rotenone-induced damage in PC12 cells but did not exhibit any significant activity.

Authors

Institutions

Publication Details

Journal
Natural Product Research
Published
2024-10-03
DOI
https://doi.org/10.1080/14786419.2024.2410420
Primary Topic
Plant chemical constituents analysis
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

A pair of enantiotropic carbazole alkaloids from the stems of Clausena emarginata C. C. Huang

Hong‐Xiang Lou, Ping Wang, Hongmin Xia, Xiao-Lei Du
Natural Product Research
Plant chemical constituents analysis
article

A pair of enantiotropic carbazole alkaloids from the stems of Clausena emarginata C. C. Huang

Hong‐Xiang Lou, Ping Wang, Hongmin Xia, Xiao-Lei Du
article en

Abstract

Two new carbazole alkaloids clauemarazole H (<b>1</b>) and clauemarazole I (<b>2</b>) were isolated from the stems of <i>Clausena emarginata</i> C. C. Huang. Their structures were confirmed by comprehensive spectroscopic analyses, and the absolute configurations were determined based on ECD experiments. The two compounds were evaluated for their neuroprotective effects against rotenone-induced damage in PC12 cells but did not exhibit any significant activity.

Natural Product ResearchVol. 40(2)
Shandong University (CN), Shandong Academy of Chinese Medicine (CN)
Zero hunger
Openalex Percentile: Top 91%
Plant chemical constituents analysis
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.