Biomarkers and Diagnostic Thresholds for Congenital Hyperinsulinism
This study suggests that a C-peptide concentration greater than 291.5 pmol/L is diagnostic of CHI in children. C-peptide appears to offer the greatest utility as a biochemical diagnostic test for CHI and could be prioritised for laboratory analysis.
Authors
- Julie Park (ORCID: https://orcid.org/0000-0002-3545-6126)
- Senthil Senniappan (ORCID: https://orcid.org/0000-0002-8001-0342)
- Catherine Collingwood
- Grace Petkovic (ORCID: https://orcid.org/0000-0003-4588-6792)
- Mohammed Didi
Institutions
- Lancashire Teaching Hospitals NHS Foundation Trust (GB)
- University of Liverpool (GB)
- Alder Hey Children's Hospital (GB)
Publication Details
- Journal
- Clinical Endocrinology
- Published
- 2024-10-03
- DOI
- https://doi.org/10.1111/cen.15137
- Citations
- 1
- Primary Topic
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Type
- article
- Field-Weighted Citation Impact
- 0.36