Stochastic Optimal Control Analysis for HBV Epidemic Model with Vaccination

In this study, we explore the concept of symmetry as it applies to the dynamics of the Hepatitis B Virus (HBV) epidemic model. By incorporating symmetric principles in the stochastic model, we ensure that the control strategies derived are not only effective but also consistent across varying conditions, and ensure the reliability of our predictions. This paper presents a stochastic optimal control analysis of an HBV epidemic model, incorporating vaccination as a pivotal control measure. We formulate a stochastic model to capture the complex dynamics of HBV transmission and its progression to acute and chronic stages. By leveraging stochastic differential equations, we examine the model’s stationary distribution and asymptotic behavior, elucidating the impact of random perturbations on disease dynamics. Optimal control theory is employed to derive control strategies aimed at minimizing the disease burden and vaccination costs. Through rigorous numerical simulations using the fourth-order Runge–Kutta method, we demonstrate the efficacy of the proposed control measures. Our findings highlight the critical role of vaccination in controlling HBV spread and provide insights into the optimization of vaccination strategies under stochastic conditions. The symmetry within the proposed model equations allows for a balanced approach to analyzing both acute and chronic stages of HBV.

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Publication Details

Journal
Symmetry
Published
2024-10-03
DOI
https://doi.org/10.3390/sym16101306
Citations
5
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
1.93
Controls
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article

Stochastic Optimal Control Analysis for HBV Epidemic Model with Vaccination

Anwarud Din, Yufeng Nie, Abdulwasea Alkhazzan, Sayed Murad Ali Shah
5 citations
Symmetry
Hepatitis B Virus Studies
1.93
article

Stochastic Optimal Control Analysis for HBV Epidemic Model with Vaccination

Anwarud Din, Yufeng Nie, Abdulwasea Alkhazzan, Sayed Murad Ali Shah
article en
5 citations

Abstract

In this study, we explore the concept of symmetry as it applies to the dynamics of the Hepatitis B Virus (HBV) epidemic model. By incorporating symmetric principles in the stochastic model, we ensure that the control strategies derived are not only effective but also consistent across varying conditions, and ensure the reliability of our predictions. This paper presents a stochastic optimal control analysis of an HBV epidemic model, incorporating vaccination as a pivotal control measure. We formulate a stochastic model to capture the complex dynamics of HBV transmission and its progression to acute and chronic stages. By leveraging stochastic differential equations, we examine the model’s stationary distribution and asymptotic behavior, elucidating the impact of random perturbations on disease dynamics. Optimal control theory is employed to derive control strategies aimed at minimizing the disease burden and vaccination costs. Through rigorous numerical simulations using the fourth-order Runge–Kutta method, we demonstrate the efficacy of the proposed control measures. Our findings highlight the critical role of vaccination in controlling HBV spread and provide insights into the optimization of vaccination strategies under stochastic conditions. The symmetry within the proposed model equations allows for a balanced approach to analyzing both acute and chronic stages of HBV.

SymmetryVol. 16(10)
Sun Yat-sen University (CN), Sana'a University (YE), Northwestern Polytechnical University (CN)
Good health and well-being
Openalex Percentile: Top 13%
Hepatitis B Virus Studies
1.93
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Stochastic Optimal Control Analysis for HBV Epidemic Model with Vaccination — Anwarud Din, Yufeng Nie, et al. · Symmetry (2024) | TGRS Research Map | TGRS