Unraveling Pneumomediastinum in COVID-19 Patients: Insights from a High-Volume-Center Case–Control Study
PNM in patients with severe COVID-19 infection is associated with younger age, elevated inflammatory markers, and extensive lung involvement, contributing to increased morbidity and prolonged hospitalization. Early detection and tailored management strategies, including optimized respiratory support and aggressive anti-inflammatory therapies, are crucial in mitigating the adverse outcomes associated with PNM. Further research is needed to validate these findings and improve clinical protocols for managing this complication.
Authors
- Khrystyna Kuzmych (ORCID: https://orcid.org/0000-0001-6399-9171)
- Mattia Paratore (ORCID: https://orcid.org/0000-0002-7546-8041)
- Filippo Lococo (ORCID: https://orcid.org/0000-0002-9383-5554)
- Marcello Covino (ORCID: https://orcid.org/0000-0002-6709-2531)
- Ludovico Abenavoli (ORCID: https://orcid.org/0000-0002-5922-1524)
- Carolina Sassorossi (ORCID: https://orcid.org/0000-0003-4654-1577)
- A Napolitano (ORCID: https://orcid.org/0000-0002-4058-5539)
- Stefano Margaritora
- Giuseppe Calabrese (ORCID: https://orcid.org/0009-0003-5070-1315)
- Annalisa Campanella (ORCID: https://orcid.org/0000-0002-7794-6641)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Agostino Gemelli University Polyclinic (IT)
- Magna Graecia University (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Diseases
- Published
- 2024-10-03
- DOI
- https://doi.org/10.3390/diseases12100242
- Primary Topic
- Pneumothorax, Barotrauma, Emphysema
- Type
- article
- Field-Weighted Citation Impact
- 0.00