Electroacupuncture ameliorates depression-like behaviors in rats with post-stroke depression by inhibiting ferroptosis in the prefrontal cortex
EA improved depression-like behaviors, mitigated mitochondrial damage, and inhibited ferroptosis in prefrontal cortex neurons. Notably, the administration of erastin further enhanced these effects. In conclusion, EA appears to improve PSD by inhibiting ferroptosis in the prefrontal cortex.
Authors
- Lihua Wu (ORCID: https://orcid.org/0000-0002-4660-4059)
- Xiaodong Feng (ORCID: https://orcid.org/0000-0003-2716-1827)
- Jing Gao (ORCID: https://orcid.org/0000-0001-9251-6204)
- Xiaolei Song
- Xinyue Zheng
- Qiongshuai Zhang (ORCID: https://orcid.org/0000-0003-0594-1654)
- Mengyu Wang (ORCID: https://orcid.org/0000-0002-7188-7126)
- Ruonan Wu
- Yixuan Feng
- Zhimin Ding
- Yuchuang Tang
- Yanyan Qin
- Mingyue Yu
- Shikui Qi
Institutions
- Guangzhou University of Chinese Medicine (CN)
- First Affiliated Hospital of Henan University (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2024-10-03
- DOI
- https://doi.org/10.3389/fnins.2024.1422638
- Citations
- 9
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.77