Evaluating Curcumin and Bromelain as Dentin Biomodifiers for Enhancing Shear Bond Strength – An Invitro study

Aim To evaluate the effect of collagen stabilizing agents like Curcumin and Bromelain enzyme on the shear bond strength of restorative resin to dentin.  Materials and Methods Thirty single rooted, non carious human mandibular premolars were selected and decoronation was done. The tooth was then mounted. Etchant was applied to the dentin samples and divided into 3 experimental groups. Group 1 (Control - Bonding agent + Composite); Group 2 (Pre-treatment with Curcumin for 30 sec + Rinsing + Bonding agent + Composite). Group 3(Pre-treatment with Bromelain enzyme for 30 sec + Rinsing + Bonding agent + Composite). Following this, total etch adhesive was applied and light. Nanohybrid composite restoration was done. Then the samples were subjected to shear bond strength. The load was applied to the bonded interface with a cross-head speed of 0.5 mm / minute until fracture occurred.  Results The mean values Shear bond strength of dentin were slightly more in bromelain enzyme (48.49), seconded by curcumin (38.80), followed by control group (27.23). The difference was statistically significant among the three different remineralising agent used.  Conclusion Bromelain enzyme showed the highest mean shear bond strength value when compared to the other experimental group.