Therapeutic effects of myrrh extract and myrrh-based silver nanoparticles on Trichinella spiralis-infected mice: parasitological, histopathological, and immunological (IFN-γ, IL-10, and MMP-9) investigations
Collectively, this study demonstrates the novel antiparasitic potential of silver nanoparticles biosynthesized with myrrh against <i>T. spiralis</i> in infected mice. The treatment was associated with moderate rise in IFN-γ gene expression and IL-10 expression, highlighting its therapeutic efficacy against <i>T. spiralis</i>.
Authors
- Fahd M. Alsharif
- Nahed Ahmed Elossily
- Naief Dahran (ORCID: https://orcid.org/0000-0003-3560-8166)
- Shaymaa M. M. Mohamed (ORCID: https://orcid.org/0000-0001-7768-0890)
- Ehab Kotb Elmahallawy (ORCID: https://orcid.org/0000-0003-4484-3678)
- Nashwa Hamad (ORCID: https://orcid.org/0000-0003-0640-5618)
- Ahmed Gareh (ORCID: https://orcid.org/0000-0002-5511-5409)
- Heba Mostafa
- Alamira Marzouk Fouad
- Ahmed Kamal Dyab (ORCID: https://orcid.org/0000-0002-4021-7904)
- Hind Alzaylaee
- Jamal Asseri
- Salwa Mahmoud Abd-Elrahman (ORCID: https://orcid.org/0000-0002-0319-7713)
- Hayat M Albisihi
- Abeer El-Sayed Mahmoud
- Ahmed Mahmoud Abd Elrahman
Institutions
- Princess Nourah bint Abdulrahman University (SA)
- Al-Azhar University (EG)
- King Abdulaziz University (SA)
- Shaqra University (SA)
- University of Jeddah (SA)
- Badr University in Cairo (EG)
- University of Córdoba (ES)
- Aswan University (EG)
- Assiut University (EG)
- Sohag University (EG)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2024-10-03
- DOI
- https://doi.org/10.3389/fvets.2024.1433964
- Citations
- 5
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 2.58
Funders
- Princess Nourah Bint Abdulrahman University