Synthesis of <i>S</i>-Alkyl Dithiocarbamates via Multicomponent Reaction of Cyclic Sulfonium Salts with CS<sub>2</sub> and Amines

A convenient and practical method for the synthesis of various <i>S</i>-alkyl dithiocarbamates through three-component reaction of sulfonium salts, CS<sub>2</sub> and amines has been developed. The reaction proceeds efficiently without any catalyst and additive under mild and open-air conditions, making it potential applications in pharmaceutical chemistry and sulfur chemistry.

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Publication Details

Journal
The Journal of Organic Chemistry
Published
2024-10-03
DOI
https://doi.org/10.1021/acs.joc.4c02063
Citations
21
Primary Topic
Sulfur-Based Synthesis Techniques
Type
article
Field-Weighted Citation Impact
5.25

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article

Synthesis of S-Alkyl Dithiocarbamates via Multicomponent Reaction of Cyclic Sulfonium Salts with CS2 and Amines

Wei Huang, S. Y. Chen, Long‐Yong Xie, Xiang-Qin Xu et al.
21 citations
The Journal of Organic Chemistry
Sulfur-Based Synthesis Techniques
5.25
article

Synthesis of S-Alkyl Dithiocarbamates via Multicomponent Reaction of Cyclic Sulfonium Salts with CS2 and Amines

Wei Huang, S. Y. Chen, Long‐Yong Xie, Xiang-Qin Xu, Yun Liu, Jia Shu, Li Yang, Yuan-Xin Jin
article en
21 citations

Abstract

A convenient and practical method for the synthesis of various <i>S</i>-alkyl dithiocarbamates through three-component reaction of sulfonium salts, CS<sub>2</sub> and amines has been developed. The reaction proceeds efficiently without any catalyst and additive under mild and open-air conditions, making it potential applications in pharmaceutical chemistry and sulfur chemistry.

The Journal of Organic ChemistryVol. 89(20)
China Three Gorges University (CN), Hunan University of Science and Engineering (CN)
National Natural Science Foundation of China, Science and Technology Program of Hunan Province
Openalex Percentile: Top 3%
Sulfur-Based Synthesis Techniques
5.25
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