Comprehensive pulmonary function analysis identifies predominant obstructive phenotype in former premature infants around one year of age

Preterm infants in the first year of life, demonstrated a high prevalence of obstructive iPFT unresponsive to bronchodilators. BPD status did not add to the degree of pulmonary impairment. These data reveal an airway-predominant pathology of the modern-era prematurity-associated lung disease. Pulmonary function screening tests at an early age may be of value in determining the presence and severity of lung disease in the preterm population. V'<sub>max</sub>FRC may provide a good assessment of pulmonary impairment in preterm infants.

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Publication Details

Journal
Pediatric Pulmonology
Published
2024-10-03
DOI
https://doi.org/10.1002/ppul.27287
Primary Topic
Neonatal Respiratory Health Research
Type
article
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article

Comprehensive pulmonary function analysis identifies predominant obstructive phenotype in former premature infants around one year of age

Avigdor Hevroni, E. Spitzer Stein, Alex Gileles‐Hillel, Ira Erlichman et al.
Pediatric Pulmonology
Neonatal Respiratory Health Research
article

Comprehensive pulmonary function analysis identifies predominant obstructive phenotype in former premature infants around one year of age

Avigdor Hevroni, E. Spitzer Stein, Alex Gileles‐Hillel, Ira Erlichman, Laurice Boursheh, Mor Zarfati
article en

Abstract

Preterm infants in the first year of life, demonstrated a high prevalence of obstructive iPFT unresponsive to bronchodilators. BPD status did not add to the degree of pulmonary impairment. These data reveal an airway-predominant pathology of the modern-era prematurity-associated lung disease. Pulmonary function screening tests at an early age may be of value in determining the presence and severity of lung disease in the preterm population. V'<sub>max</sub>FRC may provide a good assessment of pulmonary impairment in preterm infants.

Pediatric PulmonologyVol. 59(12)
Hebrew University of Jerusalem (IL), Hadassah Medical Center (IL)
Good health and well-being
Openalex Percentile: Top 68%
Neonatal Respiratory Health Research
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