Synthesis and characterization of phenethyl isothiocyanate conjugated with magnetic nanoparticles modified by tumor targeting peptide (TTP) using in cancer treatment

Conclusion:In this project, an effective method for synthesizing phenethyl isothiocyanate conjugated with magnetic nanoparticles was developed.In the second step, an anticancer drug (DTX) and a peptide derived from EGF fragments were attached to the MNPs both physically and chemically interaction.The nanoparticles were characterized using TEM, NMR, DLS, FTIR, and TGA.Additionally, peptides were characterized by LC-MS, and their structures were confirmed.The interaction between peptides and MNPs will be studied.