Revascularization of myocardial infarction without ST segment elevation in multivessel coronary artery disease

Many patients with non-ST elevation myocardial infarction have multivessel coronary artery disease, which complicates the course of the disease and is associated with fatal outcomes. Most patients with non-ST elevation myocardial infarction undergo coronary angiography and revascularization during initial hospitalization. However, the decision to perform total or incomplete revascularization and whether to perform total revascularization on admission or at the stage of its implementation is complex and must be adapted to the age, general condition of the patient and comorbidities. Sincethe majority of patients with non-STelevation myocardial infarction have multivessel disease, treatment and timing are critical components to ensure favorable outcomes. Early revascularization is associated with improved long-term patient outcomes, but the optimal approach to revascularization in patients with non-ST elevation myocardial infarction with multivessel disease remains poorly understood. However, in this patient population, a multidisciplinary cardiac approach is recommended to determine revascularization options. Published data suggest that evaluation of the risk-benefit associated with future invasive procedures should be based on an analysis of the patient's general condition and cardiovascular risk factors, the ability to identify the culprit artery, the technical feasibility of performing multivessel revascularization, and the location, degree of stenosis, and severity of lesions.Whether multivessel percutaneous coronary intervention or coronary artery bypass grafting provides better outcomes in patients with non-ST elevation myocardial infarction remains largely debatable. In this connection, it is relevant to conduct prospective studies to study the optimal revascularization strategies.