Laherradurin Inhibits Colorectal Cancer Cell Growth by Induction of Mitochondrial Dysfunction and Autophagy Induction
LAH's anticancer effects in CRC cells are driven by its disruption of mitochondrial function, triggering both autophagy and apoptosis. These findings highlight its potential as a therapeutic compound for further exploration in cancer treatment.
Authors
- Alejandro López‐Saavedra (ORCID: https://orcid.org/0000-0002-3838-4738)
- Yahir A. Loissell-Baltazar
- Carlos Pérez‐Plasencia (ORCID: https://orcid.org/0000-0002-8593-8211)
- Eloy-Andrés Pérez-Yépez (ORCID: https://orcid.org/0000-0003-2876-9463)
- Svetlana Dokudovskaya (ORCID: https://orcid.org/0000-0001-6032-622X)
- Nadia Jacobo‐Herrera (ORCID: https://orcid.org/0000-0002-1026-3774)
- Jossimar Coronel-Hernández (ORCID: https://orcid.org/0000-0001-6543-5310)
- Izamary Delgado-Waldo (ORCID: https://orcid.org/0000-0002-3688-9775)
- Mariano Martínez‐Vázquez (ORCID: https://orcid.org/0000-0003-0954-2765)
- Eduardo Pérez-Arteaga
Institutions
- Universidad Autónoma de Tlaxcala (MX)
- Centre National de la Recherche Scientifique (FR)
- Université Paris-Saclay (FR)
- Institut Gustave Roussy (FR)
- Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (MX)
- Instituto Nacional de Cancerología (MX)
- Universidad Nacional Autónoma de México (MX)
- Tecnológico de Monterrey (MX)
Publication Details
- Journal
- Cells
- Published
- 2024-10-03
- DOI
- https://doi.org/10.3390/cells13191649
- Citations
- 2
- Primary Topic
- Traditional and Medicinal Uses of Annonaceae
- Type
- article
- Field-Weighted Citation Impact
- 0.59
Funders
- Instituto Nacional de Cancerología
- Consejo Nacional de Ciencia y Tecnología
- Ligue Contre le Cancer