Integrative analysis of H&E and IHC identifies prognostic immune subtypes in HPV related oropharyngeal cancer
Integrating H&E and IHC data enhances the functional characterization of immune phenotypes of the TME with biological interpretability, and improves patient stratification in HPV( + ) OPSCC.
Authors
- Linda X. Yin (ORCID: https://orcid.org/0000-0001-8515-2051)
- Eric J. Moore (ORCID: https://orcid.org/0000-0003-1103-6212)
- Kathryn M. Van Abel (ORCID: https://orcid.org/0000-0003-0513-4203)
- Tae Hyun Hwang (ORCID: https://orcid.org/0000-0002-6668-7269)
- Sumanth Reddy Nakkireddy (ORCID: https://orcid.org/0000-0002-7771-6782)
- David M. Routman (ORCID: https://orcid.org/0000-0002-2768-003X)
- J. Daniel (ORCID: https://orcid.org/0000-0002-2957-4687)
- Kathleen R. Bartemes (ORCID: https://orcid.org/0000-0003-4561-3233)
- Chadi Nimeh Abdel‐Halim (ORCID: https://orcid.org/0000-0003-3029-6204)
- Inyeop Jang
- Minji Kim (ORCID: https://orcid.org/0009-0009-6787-0354)
- Joaquín J. García (ORCID: https://orcid.org/0000-0002-6174-3401)
- Michael Rivera (ORCID: https://orcid.org/0000-0002-9516-2023)
Institutions
- Jacksonville College (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Communications Medicine
- Published
- 2024-10-03
- DOI
- https://doi.org/10.1038/s43856-024-00604-w
- Citations
- 9
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.22
Funders
- National Cancer Institute