Epigenomic biomarkers insights in PBMCs for prognostic assessment of ECMO-treated cardiogenic shock patients
This study identifies DNA methylation features in PBMCs as potent prognostic markers for ECMO-treated CS patients. Demonstrating significant predictive accuracy for in-hospital mortality, these markers offer a substantial advancement in patient stratification and might improve treatment outcomes.
Authors
- Yih‐Sharng Chen (ORCID: https://orcid.org/0000-0003-3846-8162)
- Sung‐Liang Yu (ORCID: https://orcid.org/0000-0003-4535-9036)
- Yi‐Jing Hsiao (ORCID: https://orcid.org/0000-0001-8780-8800)
- Tsai-Hsia Hong
- Shuenn‐Wen Kuo (ORCID: https://orcid.org/0000-0001-5026-5582)
- Hsi‐Yu Yu (ORCID: https://orcid.org/0000-0001-6669-4699)
- Li‐Ming Hsu (ORCID: https://orcid.org/0000-0002-9296-344X)
- Kang‐Yi Su (ORCID: https://orcid.org/0000-0002-6538-9526)
- Chiou-Ling Cheng
- Yan-Ming Chen
- Chih-An Lin (ORCID: https://orcid.org/0000-0003-4859-1965)
- Chien‐Yu Lin
- Hsuan‐Yu Chen
- Nai‐Hsin Chi (ORCID: https://orcid.org/0000-0003-1829-6084)
- Chih-Hsien Wang
- Su-Chien Chiang
- Wen‐Je Ko
Institutions
- National Yang Ming Chiao Tung University (TW)
- National Taiwan University of Science and Technology (TW)
- National Taiwan University (TW)
- National Taiwan University Hospital (TW)
- Institute of Statistical Science, Academia Sinica (TW)
- Institute of Chemistry, Academia Sinica (TW)
- Taipei Medical University (TW)
- National Taipei University (TW)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2024-10-03
- DOI
- https://doi.org/10.1186/s13148-024-01751-6
- Citations
- 1
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 0.18
Funders
- National Science Council
- Shanghai Educational Development Foundation
- Ministry of Science and Technology, Taiwan