Exploring the therapeutic mechanisms of Yikang decoction in polycystic ovary syndrome: an integration of GEO datasets, network pharmacology, and molecular dynamics simulations
This study systematically investigates the multi-target mechanisms of YKD in the treatment of PCOS, with preliminary verification provided through molecular docking and MD. The findings offer compelling evidence supporting the efficacy of YKD in treating PCOS.
Authors
- Lei Chen (ORCID: https://orcid.org/0000-0002-4091-6078)
- Xi Liu (ORCID: https://orcid.org/0000-0002-8700-632X)
- Miao Jiang (ORCID: https://orcid.org/0000-0002-3681-9494)
- Yun Sun
- Wenpin Cai (ORCID: https://orcid.org/0000-0002-2819-6389)
- LiXuan Gao
- Mojinzi Chen
Institutions
- Zhejiang Chinese Medical University (CN)
- Wenzhou Medical University (CN)
- Wenzhou Hospital of Traditional Chinese Medicine (CN)
- Fanjingshan National Nature Reserve (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2024-10-03
- DOI
- https://doi.org/10.3389/fmed.2024.1455964
- Citations
- 5
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.69