Big Heart, Small Shoes: Heart Failure in Systemic Lupus Erythematosus, More Than Lupus Cardiac Involvement

Acromegaly is a rare endocrine disorder characterized by chronic elevation of growth hormone and insulin-like growth factor-1, leading to enlargement of organs and soft tissues. Cardiovascular disease is the most frequent comorbidity and the most common cause of death in patients with acromegaly. We report a rare case of a 35-year-old woman with heart failure caused by concomitant systemic lupus erythematosus and acromegaly. Initially, the early onset of cardiac insufficiency and ventricular enlargement was attributed to the systemic lupus erythematosus, but it did not respond well to the treatment.

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Publication Details

Journal
CJC Open
Published
2024-10-03
DOI
https://doi.org/10.1016/j.cjco.2024.09.016
Primary Topic
Systemic Lupus Erythematosus Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Big Heart, Small Shoes: Heart Failure in Systemic Lupus Erythematosus, More Than Lupus Cardiac Involvement

Mengzhuo Cao, Yangzhong Zhou, Qian Wang, Yining Wang et al.
CJC Open
Systemic Lupus Erythematosus Research
article

Big Heart, Small Shoes: Heart Failure in Systemic Lupus Erythematosus, More Than Lupus Cardiac Involvement

Mengzhuo Cao, Yangzhong Zhou, Qian Wang, Yining Wang, Shuang Zhou, Xiaohang Liu, Mengtao Li, Xinhui Ning, Shenke Liu, Hui Zhang
article en

Abstract

Acromegaly is a rare endocrine disorder characterized by chronic elevation of growth hormone and insulin-like growth factor-1, leading to enlargement of organs and soft tissues. Cardiovascular disease is the most frequent comorbidity and the most common cause of death in patients with acromegaly. We report a rare case of a 35-year-old woman with heart failure caused by concomitant systemic lupus erythematosus and acromegaly. Initially, the early onset of cardiac insufficiency and ventricular enlargement was attributed to the systemic lupus erythematosus, but it did not respond well to the treatment.

CJC OpenVol. 7(1)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN), Beijing Hospital (CN)
Peking Union Medical College Hospital
Good health and well-being
Openalex Percentile: Top 70%
Systemic Lupus Erythematosus Research
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Big Heart, Small Shoes: Heart Failure in Systemic Lupus Erythematosus, More Than Lupus Cardiac Involvement — Mengzhuo Cao, Yangzhong Zhou, et al. · CJC Open (2024) | TGRS Research Map | TGRS