The efficacy of antimicrobial solutions against multispecies bacterial biofilm with or without negative pressure wound therapy in an <i>in vitro</i> wound model
Prontosan significantly reduced biofilm cell numbers, with better efficacy over 48 than 24 h, emphasizing the necessity for persistent and robust treatment. NPWT enhanced the effectiveness of Prontosan instillation. However, NPWT alone or combined with Vashe showed limited efficacy and difficulty when combating the multispecies biofilm in vitro.
Authors
- Karen Vickery (ORCID: https://orcid.org/0000-0003-0998-1370)
- Shamaila Tahir (ORCID: https://orcid.org/0000-0001-6749-9801)
- Honghua Hu (ORCID: https://orcid.org/0000-0002-3749-4089)
- Farhana Parvin
- M.-X. Wang
- Anand K. Deva (ORCID: https://orcid.org/0000-0002-0314-7177)
Institutions
- UNSW Sydney (AU)
- Jinhua Academy of Agricultural Sciences (CN)
- Zhejiang University (CN)
- Macquarie University (AU)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2024-10-03
- DOI
- https://doi.org/10.1093/jac/dkae338
- Primary Topic
- Bacterial biofilms and quorum sensing
- Type
- article
- Field-Weighted Citation Impact
- 0.00