Deep Brain Stimulation Withdrawal Syndrome, a Rare Life-Threatening Condition in Neurology and Neurosurgery
The article addresses an acute condition associated with an abrupt cessation of neurostimulation of deep brain structures, which is manifested by acute hypokinesia and rigidity with further development of akinesia, anarthria and dysphagia. This may result in the need for emergency hospitalization and admission to an intensive care unit. The article presents literature review and clinical case reports. We discuss causes and approaches to the prevention and management of acute decompensation in patients with Parkinson's disease associated with abrupt deep brain stimulation cessation.
Authors
- Anna Gamaleya (ORCID: https://orcid.org/0000-0002-6412-8148)
- Anna A. Poddubskaya (ORCID: https://orcid.org/0000-0002-5776-3442)
- Alexey Tomskiy (ORCID: https://orcid.org/0000-0002-2120-0146)
- N.V. Fedorova (ORCID: https://orcid.org/0000-0003-2168-2138)
- D. G. Kesarev
- Ekaterina Bril (ORCID: https://orcid.org/0000-0002-6524-4490)
Institutions
- Russian Medical Academy of Continuous Professional Education (RU)
- Burdenko Neurosurgery Institute (RU)
- State Scientific Center of the Russian Federation - Federal Medical Biophysical Center named after A.I. Burnazyan (RU)
Publication Details
- Journal
- Annals of Clinical and Experimental Neurology
- Published
- 2024-10-03
- DOI
- https://doi.org/10.17816/acen.1095
- Citations
- 2
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.74