International, Multi-Institutional Evaluation of Practice Patterns and Outcomes for Recurrent and Metastatic Sinonasal Undifferentiated Carcinoma
To our knowledge, this is the first study addressing metastatic and recurrent SNUC based on a large patient cohort. Orbital extension of the primary SNUC may predict a higher probability of recurrence following treatment, suggesting the possible utility of a more aggressive treatment in this subgroup of patients. A heterogenous patient population and wide variability in management emphasize the challenges in standardizing care; however, dismal survival rates demonstrate the necessity for further evaluation of current approaches to improve evidence-based recommendations.
Authors
- Matt Lechner (ORCID: https://orcid.org/0000-0002-7123-0773)
- Fausto Sessa (ORCID: https://orcid.org/0000-0002-6633-536X)
- Davide Lombardi (ORCID: https://orcid.org/0000-0001-8430-4789)
- Mario Turri–Zanoni (ORCID: https://orcid.org/0000-0002-3678-9088)
- Alessandro Franchi (ORCID: https://orcid.org/0000-0002-1332-5838)
- Piero Nicolai (ORCID: https://orcid.org/0000-0003-0443-3519)
- Shirley Y. Su (ORCID: https://orcid.org/0000-0002-3903-8204)
- Arushi Mahajan (ORCID: https://orcid.org/0009-0007-6948-0689)
- Marco Ferrari (ORCID: https://orcid.org/0000-0002-4023-0121)
- Paolo Bossi (ORCID: https://orcid.org/0000-0003-0135-0224)
- Paolo Castelnuovo (ORCID: https://orcid.org/0000-0002-5184-6140)
- Simonetta Battocchio (ORCID: https://orcid.org/0000-0002-4868-0397)
- Erin L. McKean (ORCID: https://orcid.org/0000-0002-7026-0903)
- Carla Facco
- Laura Ardighieri (ORCID: https://orcid.org/0000-0002-6200-9671)
- Valerie J. Lund (ORCID: https://orcid.org/0000-0002-2503-2215)
- Amrita Jay
- Davide Mattavelli (ORCID: https://orcid.org/0000-0001-7023-6746)
- Nyall R. London (ORCID: https://orcid.org/0000-0002-2902-4407)
- Anirudh Saraswathula (ORCID: https://orcid.org/0000-0001-7745-3049)
- Vittorio Rampinelli (ORCID: https://orcid.org/0000-0002-0901-6266)
- Ehab Y. Hanna (ORCID: https://orcid.org/0000-0003-3241-2440)
- Martin Förster (ORCID: https://orcid.org/0000-0003-3876-7269)
- Jacklyn Liu (ORCID: https://orcid.org/0000-0003-1748-0314)
- Dawn Carnell (ORCID: https://orcid.org/0000-0002-2898-3219)
- Mohammed Ullah (ORCID: https://orcid.org/0000-0003-3263-983X)
- Yoko Takahashi
Institutions
- University of Pisa (IT)
- University of Insubria (IT)
- National Institutes of Health (US)
- Humanitas University (IT)
- University College London Hospitals NHS Foundation Trust (GB)
- The University of Texas MD Anderson Cancer Center (US)
- University of Padua (IT)
- Johns Hopkins University (US)
- University of Michigan (US)
- Johns Hopkins Medicine (US)
- Royal London Hospital (GB)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- Michigan United (US)
- National Cancer Institute (US)
- Center for Cancer Research (US)
- National Hospital for Neurology and Neurosurgery (GB)
- Eastman Dental Hospital (GB)
- IRCCS Humanitas Research Hospital (IT)
- University College London (GB)
- University of Brescia (IT)
Publication Details
- Journal
- Journal of Neurological Surgery Part B Skull Base
- Published
- 2024-10-03
- DOI
- https://doi.org/10.1055/s-0044-1791573
- Citations
- 1
- Primary Topic
- Head and Neck Surgical Oncology
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- National Institutes of Health
- National Cancer Institute
- National Institute on Deafness and Other Communication Disorders