Targeted Acidosis Mediated Delivery of Antigenic MHC-Binding Peptides
CSIINFEKL Retains Potent MHC Binding and T Cell ActivationTreatment of pHLIP-CysOVA at low pH improves T cell activation.-galactosidase pH(low) insertion peptides (pHLIP) selectively insert into the membrane of cells in acidic microenvironments -a hallmark of cancer biology.
Authors
- Emily Ankrom
- Damien Thévenin (ORCID: https://orcid.org/0000-0002-1866-0694)
- Marcos M. Pires (ORCID: https://orcid.org/0000-0002-5676-0725)
- Joey J. Kelly
- Sarah E. Newkirk
Publication Details
- Published
- 2024-09-20
- DOI
- https://doi.org/10.17952/37eps.2024.p1126
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00