Exploring genetic and immune cell dynamics in systemic lupus erythematosus patients with Epstein–Barr virus infection via machine learning
This study identified IFI27 as a key gene for SLE patients with EBV infection, influencing CD4 CTL and B cell subtypes. These findings enhance the understanding of the molecular mechanisms linking SLE and EBV infection, providing potential targets for diagnostic and therapeutic strategies.
Authors
- Li Sun (ORCID: https://orcid.org/0009-0004-1866-3731)
- Jiajun Gui (ORCID: https://orcid.org/0009-0008-2328-4030)
- Jianxin Tu (ORCID: https://orcid.org/0000-0001-9273-5351)
- Mengyuan Fang
- Xiaowei Chen (ORCID: https://orcid.org/0000-0001-6426-5399)
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2024-10-03
- DOI
- https://doi.org/10.1093/rheumatology/keae537
- Citations
- 2
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Universidade de Macau
- Science Research Foundation of Zhejiang Province