Systolic blood pressure variability in late-life predicts cognitive trajectory and risk of Alzheimer’s disease
These findings supported that maintaining stable SBP in late life helped lower the risk of AD, partially by modulating amyloid pathology, cerebral metabolism, and cerebrovascular health.
Authors
- Ruotong Wang (ORCID: https://orcid.org/0000-0001-9758-7458)
- Lan Tan (ORCID: https://orcid.org/0000-0002-8759-7588)
- Xiaolu Li (ORCID: https://orcid.org/0000-0002-9845-1584)
- Chen‐Chen Tan
- Wei Xu (ORCID: https://orcid.org/0000-0002-3310-5875)
Institutions
- Qingdao University (CN)
- Dalian Medical University (CN)
- Qingdao Municipal Hospital (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2024-10-03
- DOI
- https://doi.org/10.3389/fnagi.2024.1448034
- Citations
- 2
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- U.S. Department of Defense
- Alzheimer's Association
- Bristol-Myers Squibb
- Eli Lilly and Company
- Pfizer
- Biogen
- University of Southern California
- Meso Scale Diagnostics
- Alzheimer's Disease Neuroimaging Initiative
- BioClinica
- Novartis Pharmaceuticals Corporation
- Northern California Institute for Research and Education
- Eisai
- Servier
- H. Lundbeck A/S
- IXICO
- National Institutes of Health
- Genentech
- Canadian Institutes of Health Research
- Janssen Alzheimer Immunotherapy Research And Development