Exploring The Relationship Between Metabolic Syndrome And Renal Dysfunction In A Hospital-Based Indian Cohort

Background: Metabolic Syndrome (MetS) is a cluster of conditions that increase the risk of cardiovascular disease and other health problems. This retrospective study aims to investigate the relationship between MetS components and renal function parameters in a hospital based cohort. Methods: The National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III) recommendations classified 300 people aged 35–65 as having or not having MetS. Renal function, lipids, and glucose were measured. Chi-square tests and one-way ANOVA were used to examine MetS and renal function. Results: MetS was found in 40% of study participants. Age group significantly correlated with MetS status (χ2 = 23.31, p = 0.001), with higher prevalence in older age groups. There was no significant correlation between gender and MetS status (χ2 = 0.795, p = 0.373). FBS levels differed considerably across groups (p < 0.001), while HDL levels were negatively linked with MetS components (p < 0.001). Both serum creatinine and urine albumin levels were considerably increased in patients with more MetS components (p = 0.001 and p < 0.001, respectively), suggesting renal impairment. Conclusion: This emphasises the importance of early MetS diagnosis and treatment to prevent kidney problems. Future research should focus longitudinal analyses to better understand MetS-renal health cause-and-effect links.