Comparative analysis of porcine-uterine decellularization for bioactive-molecule preservation and DNA removal
Our findings enhance the nuanced understanding of DNA removal, GAG preservation, microstructural alteration, and protein decomposition in decellularized uterine extracellular matrix, while highlighting the importance of decellularization protocols designed for intended applications. This study along with our findings represents meaningful progress for advancing the field of uterine transplantation and related tissue engineering/regenerative medicine.
Authors
- Amin Babaei‐Ghazvini (ORCID: https://orcid.org/0000-0001-9740-5626)
- Kobra Tahermanesh (ORCID: https://orcid.org/0000-0003-2969-3085)
- Ildikó Badea (ORCID: https://orcid.org/0000-0003-0500-4476)
- Abbas Fazel Anvari‐Yazdi (ORCID: https://orcid.org/0000-0003-3083-1457)
- Bishnu Acharya (ORCID: https://orcid.org/0000-0003-2442-0969)
- Daniel Chen (ORCID: https://orcid.org/0000-0002-4716-549X)
- Maryam Ejlali
- Daniel J MacPhee
Institutions
- Iran University of Medical Sciences (IR)
- University of Saskatchewan (CA)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2024-10-02
- DOI
- https://doi.org/10.3389/fbioe.2024.1418034
- Citations
- 8
- Primary Topic
- Tissue Engineering and Regenerative Medicine
- Type
- article
- Field-Weighted Citation Impact
- 4.58
Funders
- Mitacs
- Natural Sciences and Engineering Research Council of Canada