Hepatic retinol dehydrogenase 11 dampens stress associated with the maintenance of cellular cholesterol levels
Taken together, these findings suggest that RDH11 likely plays a role in protecting cells against the cellular toxicity that can arise as a by-product of endogenous cellular cholesterol synthesis.
Authors
- Darren C. Henstridge (ORCID: https://orcid.org/0000-0003-4988-767X)
- Michael F. Keating (ORCID: https://orcid.org/0000-0002-0767-1144)
- Peter J. Meikle (ORCID: https://orcid.org/0000-0002-2593-4665)
- Paul Gregorevic (ORCID: https://orcid.org/0000-0002-7418-8945)
- Natalie A. Mellett (ORCID: https://orcid.org/0000-0002-9442-3009)
- Kevin I. Watt (ORCID: https://orcid.org/0000-0001-7475-4487)
- Eleanor A.M. Gould
- Anna C. Calkin (ORCID: https://orcid.org/0000-0002-9861-0602)
- Brian G. Drew (ORCID: https://orcid.org/0000-0002-7839-9467)
- Yingying Liu (ORCID: https://orcid.org/0000-0002-4061-9057)
- Christine Yang (ORCID: https://orcid.org/0000-0003-2800-6159)
- Mitchell T Hallam
Institutions
- University of Tasmania (AU)
- Baker Heart and Diabetes Institute (AU)
- The University of Melbourne (AU)
- Murdoch Children's Research Institute (AU)
- Monash University (AU)
Publication Details
- Journal
- Molecular Metabolism
- Published
- 2024-10-02
- DOI
- https://doi.org/10.1016/j.molmet.2024.102041
- Citations
- 1
- Primary Topic
- Retinoids in leukemia and cellular processes
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- National Heart Foundation of Australia
- University of Melbourne
- State Government of Victoria
- Medical Research Council
- National Health and Medical Research Council