Genetic variants of LRRC8C, OAS2, and CCL25 in the T cell exhaustion-related genes are associated with non-small cell lung cancer survival
Our findings suggested that these functional SNPs in the T cell exhaustion-related genes may be prognostic predictors for survival of NSCLC patients, possibly via a mechanism of modulating corresponding gene expression.
Authors
- Xiao‐Zhun Tang
- Sheng Luo (ORCID: https://orcid.org/0000-0003-4214-5809)
- Mulong Du (ORCID: https://orcid.org/0000-0002-2733-6490)
- Huilin Wang (ORCID: https://orcid.org/0000-0003-3061-0806)
- David C. Christiani (ORCID: https://orcid.org/0000-0002-0301-0242)
- Hongliang Liu (ORCID: https://orcid.org/0000-0001-7639-0904)
- Guojun Lu (ORCID: https://orcid.org/0000-0001-8753-4926)
- Qingyi Wei
Institutions
- Harvard University (US)
- Guangxi Medical University (CN)
- Duke University (US)
- Massachusetts General Hospital (US)
- Nanjing Brain Hospital (CN)
- Duke Medical Center (US)
- Nanjing Chest Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-02
- DOI
- https://doi.org/10.3389/fimmu.2024.1455927
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.28
Funders
- National Institutes of Health
- Programme Development Grants
- National Cancer Institute
- Duke Cancer Institute