A single amplified genome catalog reveals the dynamics of mobilome and resistome in the human microbiome
The difference in taxonomic composition between SAGs and MAGs indicates that combining both methods would be effective in expanding the genome catalog. By connecting mobilomes and resistomes in individual samples, SAGs could meticulously chart a dynamic network of ARGs on MGEs, pinpointing potential ARG reservoirs and their spreading patterns in the microbial community. Video Abstract.
Authors
- Kazuma Kamata
- Koji Arikawa
- Ayumi Matsuhashi
- Tatsuya Saeki
- Masahito Hosokawa (ORCID: https://orcid.org/0000-0002-7070-4690)
- Taruho Endoh
- Tetsuro Kawano-Sugaya (ORCID: https://orcid.org/0000-0001-5401-4414)
Institutions
- Waseda University (JP)
- The Open University of Japan (JP)
Publication Details
- Journal
- Microbiome
- Published
- 2024-10-02
- DOI
- https://doi.org/10.1186/s40168-024-01903-z
- Citations
- 14
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 3.27
Funders
- Tokyo Metropolitan Small and Medium Enterprise Support Center