A fundus vessel segmentation method based on double skip connections combined with deep supervision
Extensive experiments on publicly available multimodal fundus datasets such as DRIVE, CHASE_DB1, and ROSE-1 demonstrate that the DS2TUNet model attains F1-scores of 0.8195, 0.8362, and 0.8425, with Accuracy of 0.9664, 0.9741, and 0.9557, Sensitivity of 0.8071, 0.8101, and 0.8586, and Specificity of 0.9823, 0.9869, and 0.9713, respectively. Additionally, the model also exhibits excellent test performance on the clinical fundus dataset CSC, with F1-score of 0.7757, Accuracy of 0.9688, Sensitivity of 0.8141, and Specificity of 0.9801 based on the weight trained on the CHASE_DB1 dataset. These results comprehensively validate that the proposed method obtains good performance in fundus vessel segmentation, thereby aiding clinicians in the further diagnosis and treatment of fundus diseases in terms of effectiveness and feasibility.
Authors
- Xiangzhong Xu
- Fen Zhou (ORCID: https://orcid.org/0000-0003-2357-4819)
- Zhipeng Yan (ORCID: https://orcid.org/0000-0001-7812-8555)
- Qingyou Liu (ORCID: https://orcid.org/0000-0003-0771-1115)
- Cheng Wan (ORCID: https://orcid.org/0000-0002-9818-0139)
- Jianguo Xu (ORCID: https://orcid.org/0000-0001-7419-4467)
- Jianxin Shen (ORCID: https://orcid.org/0000-0002-6774-1095)
- Jin Yao (ORCID: https://orcid.org/0000-0002-9589-3555)
Institutions
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Nanjing University of Aeronautics and Astronautics (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2024-10-03
- DOI
- https://doi.org/10.3389/fcell.2024.1477819
- Citations
- 1
- Primary Topic
- Retinal Imaging and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.40
Funders
- National Natural Science Foundation of China
- Nanjing University of Aeronautics and Astronautics
- China Scholarship Council
- Nanjing Medical University
- Nanjing University
- Fundamental Research Funds for the Central Universities