The role of lactylation in plasma cells and its impact on rheumatoid arthritis pathogenesis: insights from single-cell RNA sequencing and machine learning

This study highlights the critical role of lactylation in plasma cells for RA pathogenesis and identifies potential biomarkers and therapeutic targets, which may offer insights for future therapeutic strategies.

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Publication Details

Journal
Frontiers in Immunology
Published
2024-10-03
DOI
https://doi.org/10.3389/fimmu.2024.1453587
Citations
15
Primary Topic
Systemic Lupus Erythematosus Research
Type
article
Field-Weighted Citation Impact
7.05
Controls
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article

The role of lactylation in plasma cells and its impact on rheumatoid arthritis pathogenesis: insights from single-cell RNA sequencing and machine learning

Tianbao Wang, Weicong Fu, Qining Yang, Tiejun Shi et al.
15 citations
Frontiers in Immunology
Systemic Lupus Erythematosus Research
7.05
article

The role of lactylation in plasma cells and its impact on rheumatoid arthritis pathogenesis: insights from single-cell RNA sequencing and machine learning

Tianbao Wang, Weicong Fu, Qining Yang, Tiejun Shi, Yehong Lu
article en
15 citations

Abstract

This study highlights the critical role of lactylation in plasma cells for RA pathogenesis and identifies potential biomarkers and therapeutic targets, which may offer insights for future therapeutic strategies.

Frontiers in ImmunologyVol. 15
Jinhua Central Hospital (CN)
Openalex Percentile: Top 2%
Systemic Lupus Erythematosus Research
7.05
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