scRNA+TCR-seq reveals the pivotal role of dual receptor T lymphocytes in the pathogenesis of Kawasaki disease and during IVIG treatment
Dual TCR T lymphocytes, especially dual TCR CD8 T cells and Treg cells, play crucial roles in the pathogenesis of KD and during IVIG treatment, providing strong support for further elucidating KD pathogenesis and optimizing treatment strategies.
Authors
- Xinsheng Yao
- Jun Li (ORCID: https://orcid.org/0000-0002-5190-0733)
- Yi Yuan (ORCID: https://orcid.org/0009-0006-6519-5314)
- Xing Zhang
- Li-Ping Mou
- Yuanyuan Xu (ORCID: https://orcid.org/0009-0008-5750-445X)
- Linhu Hui
Institutions
- Zunyi Medical University (CN)
- Kunming Children's Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-03
- DOI
- https://doi.org/10.3389/fimmu.2024.1457687
- Citations
- 11
- Primary Topic
- Kawasaki Disease and Coronary Complications
- Type
- article
- Field-Weighted Citation Impact
- 6.30
Funders
- National Natural Science Foundation of China
- Kunming Medical University