An analysis of the clinical significance of the TKI-resistant gene ZNF687 for hepatocellular carcinoma patients

ZNF687 represents a TKI-resistant and growth-dependent gene for HCC, the overexpression of which indicates poor OS for HCC patients. Additionally, ZNF687 is expected to be a druggable target for overcoming TKI resistance, and chaetocin may be a candidate therapeutic compound for ZNF687.

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Publication Details

Journal
Advances in Clinical and Experimental Medicine
Published
2024-10-02
DOI
https://doi.org/10.17219/acem/188425
Primary Topic
Chemical Synthesis and Analysis
Type
article
Field-Weighted Citation Impact
0.00

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article

An analysis of the clinical significance of the TKI-resistant gene ZNF687 for hepatocellular carcinoma patients

Xuan-Fei Wang, Rong‐Quan He, Guan-Lan Zhang, Jian‐Di Li et al.
Advances in Clinical and Experimental Medicine
Chemical Synthesis and Analysis
article

An analysis of the clinical significance of the TKI-resistant gene ZNF687 for hepatocellular carcinoma patients

Xuan-Fei Wang, Rong‐Quan He, Guan-Lan Zhang, Jian‐Di Li, Zhi‐Guang Huang, Gang Chen, Hong Zhao, Songyang Zhong, Feifei Wu, Kun‐Jun Wu, Ying-Yu Mo, Yi-Si Qin, Jifeng He
article en

Abstract

ZNF687 represents a TKI-resistant and growth-dependent gene for HCC, the overexpression of which indicates poor OS for HCC patients. Additionally, ZNF687 is expected to be a druggable target for overcoming TKI resistance, and chaetocin may be a candidate therapeutic compound for ZNF687.

Advances in Clinical and Experimental MedicineVol. 34(5)
Guangxi Medical University (CN), First Affiliated Hospital of GuangXi Medical University (CN)
Guangxi Medical University
Good health and well-being
Openalex Percentile: Top 85%
Chemical Synthesis and Analysis
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An analysis of the clinical significance of the TKI-resistant gene ZNF687 for hepatocellular carcinoma patients — Xuan-Fei Wang, Rong‐Quan He, et al. · Advances in Clinical and Experimental Medicine (2024) | TGRS Research Map | TGRS