Optogenetic estimation of synaptic connections in brain slices

The proposed method simplifies the estimation of connection probabilities, which is expected to advance the study of neural circuits in conditions such as autism and schizophrenia where connection probabilities vary. Furthermore, this approach is applicable not only to local circuits but also to long-range connections, thus increasing experimental throughput.

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Publication Details

Journal
Journal of Neuroscience Methods
Published
2024-10-02
DOI
https://doi.org/10.1016/j.jneumeth.2024.110298
Citations
4
Primary Topic
Photoreceptor and optogenetics research
Type
article
Field-Weighted Citation Impact
1.07

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article

Optogenetic estimation of synaptic connections in brain slices

Kashima Tetsuhiko, Takuya Sasaki, Yuji Ikegaya
4 citations
Journal of Neuroscience Methods
Photoreceptor and optogenetics research
1.07
article

Optogenetic estimation of synaptic connections in brain slices

Kashima Tetsuhiko, Takuya Sasaki, Yuji Ikegaya
article en
4 citations

Abstract

The proposed method simplifies the estimation of connection probabilities, which is expected to advance the study of neural circuits in conditions such as autism and schizophrenia where connection probabilities vary. Furthermore, this approach is applicable not only to local circuits but also to long-range connections, thus increasing experimental throughput.

Journal of Neuroscience MethodsVol. 412
Tohoku University (JP), Tohoku Medical and Pharmaceutical University (JP), National Institute of Information and Communications Technology (JP)
Japan Agency for Medical Research and Development, Japan Science and Technology Corporation, Japan Society for the Promotion of Science
Openalex Percentile: Top 24%
Photoreceptor and optogenetics research
1.07
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