MMP7, Regulated by c-Jun, is Involved in Oral Squamous Cell Carcinoma and Associated with Cancer-Related Fibroblasts Infiltration
MMP7 has been proven to be a key protein in the development of OSCC, and has the potential to become a biological marker and therapeutic target. It has been found that c-Jun could bind to the MMP7 promoter region, and the silencing or overexpression of c-Jun can positively regulate the expression of MMP7.
Authors
- Xuqian Liu (ORCID: https://orcid.org/0000-0002-4769-8093)
- Minhai Nie
- Xiaohong Chen (ORCID: https://orcid.org/0000-0002-9797-8384)
- Jian Wei (ORCID: https://orcid.org/0009-0004-2842-7767)
- Lijuan Huang (ORCID: https://orcid.org/0000-0003-2037-4176)
- Yiwen Xu (ORCID: https://orcid.org/0009-0004-1892-0881)
- Sen Yang (ORCID: https://orcid.org/0000-0001-9574-3330)
- Xiaoxi Jiang
Institutions
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- Suizhou Central Hospital (CN)
- Mianyang Institute of Traditional Chinese Medicine (CN)
- Sichuan Academy of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Current Cancer Drug Targets
- Published
- 2024-10-02
- DOI
- https://doi.org/10.2174/0115680096309161240821171847
- Primary Topic
- Oral and Maxillofacial Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00