Novel Quinoline Nitrate Derivatives: Synthesis, Characterization, and Evaluation of their Anticancer Activity with a Focus on Molecular Docking and NO Release
The synthesized quinoline nitrate derivatives showed promising anticancer activity, with compound 6g standing out as a potential lead compound. The correlation between molecular docking, NO release, and anticancer activity suggests the importance of specific structural features in the design of effective anticancer agents.
Authors
- Naresh Panigrahi (ORCID: https://orcid.org/0000-0002-6996-3660)
- Venkata Sowjanya Thanneeru
Institutions
- GITAM University (IN)
Publication Details
- Journal
- Anti-Cancer Agents in Medicinal Chemistry
- Published
- 2024-10-02
- DOI
- https://doi.org/10.2174/0118715206315415240830052608
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 0.00