Extracellular vesicles bearing serum amyloid A1 exacerbate neuroinflammation after intracerebral haemorrhage
Our findings provide compelling evidence implicating EVs and their cargo proteins in ICH pathogenesis. SAA1 emerges as a potential therapeutic target for mitigating neuroinjury and neuroinflammation following ICH.
Authors
- Shihe Jiang (ORCID: https://orcid.org/0000-0001-8542-2277)
- Haoxiao Chang (ORCID: https://orcid.org/0000-0001-6338-7562)
- Meng Yuan (ORCID: https://orcid.org/0000-0003-0856-8381)
- Xiaoping Ren (ORCID: https://orcid.org/0000-0003-0602-7055)
- Ningning Wang (ORCID: https://orcid.org/0000-0001-7883-4556)
- Wei‐Na Jin
- Huimin Zhu (ORCID: https://orcid.org/0000-0002-4340-1125)
- Ying Zhang (ORCID: https://orcid.org/0009-0007-8359-9897)
- Yingying Chang
Institutions
- Tianjin Medical University General Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Third Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Stroke and Vascular Neurology
- Published
- 2024-10-02
- DOI
- https://doi.org/10.1136/svn-2024-003525
- Citations
- 4
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 1.48
Funders
- National Natural Science Foundation of China