Exosomes-mediated delivery of miR-486-3p alleviates neuroinflammation via SIRT2-mediated inhibition of mitophagy after subarachnoid hemorrhage
Exo/miR treatment attenuates neuroinflammation after SAH by inhibiting SIRT2 expression and stimulating mitophagy, suggesting potential clinical applications.
Authors
- Bin Sheng (ORCID: https://orcid.org/0000-0003-4601-446X)
- Jia-Qing Sun
- Chun‐Hua Hang (ORCID: https://orcid.org/0000-0001-8687-7599)
- Sen Gao (ORCID: https://orcid.org/0000-0003-2134-6804)
- Jin Dong
- Niansheng Lai (ORCID: https://orcid.org/0000-0001-5695-1743)
- Yan Zhou (ORCID: https://orcid.org/0000-0002-8822-5276)
- Wei Li (ORCID: https://orcid.org/0000-0002-9258-3500)
- Xiangxin Chen (ORCID: https://orcid.org/0009-0008-5254-5797)
- Lingyun Wu (ORCID: https://orcid.org/0000-0003-4989-8184)
- Yang Liu (ORCID: https://orcid.org/0000-0002-4708-2985)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Xuzhou Medical College (CN)
- Nanjing Drum Tower Hospital (CN)
- First Affiliated Hospital of Wannan Medical College (CN)
Publication Details
- Journal
- Stroke and Vascular Neurology
- Published
- 2024-10-02
- DOI
- https://doi.org/10.1136/svn-2024-003509
- Citations
- 11
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 2.57
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangsu Province