Understanding the interaction forces between shield-triggered autoinjectors and skin: an in-depth noninvasive study

The findings confirm that an increase in shield length at the point of activation reduces skin friction with the housing, resulting in less force loss and a lower device activation force perceived by the user. Force loss can be further reduced by standing up. Understanding device-tissue interactions will support development of better AIs with fewer user failures.

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Publication Details

Journal
Expert Opinion on Drug Delivery
Published
2024-10-02
DOI
https://doi.org/10.1080/17425247.2024.2411435
Primary Topic
Cellular Mechanics and Interactions
Type
article
Field-Weighted Citation Impact
0.00

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article

Understanding the interaction forces between shield-triggered autoinjectors and skin: an in-depth noninvasive study

Dan Nørtoft Sørensen, Anne-Sofie Madsen Staples, Hanaa Abuo-Chalih
Expert Opinion on Drug Delivery
Cellular Mechanics and Interactions
article

Understanding the interaction forces between shield-triggered autoinjectors and skin: an in-depth noninvasive study

Dan Nørtoft Sørensen, Anne-Sofie Madsen Staples, Hanaa Abuo-Chalih
article en

Abstract

The findings confirm that an increase in shield length at the point of activation reduces skin friction with the housing, resulting in less force loss and a lower device activation force perceived by the user. Force loss can be further reduced by standing up. Understanding device-tissue interactions will support development of better AIs with fewer user failures.

Expert Opinion on Drug DeliveryVol. 21(10)
University of Copenhagen (DK), Novo Nordisk (Denmark) (DK), Technical University of Denmark (DK)
Innovationsfonden, Novo Nordisk, Innovation Fund
Zero hunger
Openalex Percentile: Top 82%
Cellular Mechanics and Interactions
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