Bufalin Regulates STAT3 Signaling Pathway to Inhibit Corneal Neovascularization and Fibrosis After Alkali Burn in Rats

This study demonstrated that BU inhibits CoNV, fibrosis, and inflammation by modulating the STAT3 signaling pathway, elucidating the intrinsic mechanism of its protective effect. BU has great potential in the treatment of CoNV caused by corneal alkali burns.

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Publication Details

Journal
Current Eye Research
Published
2024-10-02
DOI
https://doi.org/10.1080/02713683.2024.2408392
Citations
1
Primary Topic
Corneal Surgery and Treatments
Type
article
Field-Weighted Citation Impact
0.40

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OCT
article

Bufalin Regulates STAT3 Signaling Pathway to Inhibit Corneal Neovascularization and Fibrosis After Alkali Burn in Rats

Yan Deng, Lu Shi, Ying Lu, Xiaoyan Xiong et al.
1 citations
Current Eye Research
Corneal Surgery and Treatments
0.40
article

Bufalin Regulates STAT3 Signaling Pathway to Inhibit Corneal Neovascularization and Fibrosis After Alkali Burn in Rats

Yan Deng, Lu Shi, Ying Lu, Xiaoyan Xiong, Xiaolong Yin, Hongping Chen, Chao Wu
article en
1 citations

Abstract

This study demonstrated that BU inhibits CoNV, fibrosis, and inflammation by modulating the STAT3 signaling pathway, elucidating the intrinsic mechanism of its protective effect. BU has great potential in the treatment of CoNV caused by corneal alkali burns.

Current Eye ResearchVol. 50(2)
Nanchang University (CN), Second Affiliated Hospital of Nanchang University (CN)
Education Department of Jiangxi Province
Zero hunger
Openalex Percentile: Top 34%
Corneal Surgery and Treatments
0.40
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