The Usefulness of the Regression-Based Normed SKT Short Cognitive Performance Test in Detecting Cognitive Impairment in a Community Sample
<b>Background:</b> The SKT is a short cognitive performance test designed to assess impairments in memory and cognitive abilities such as attention and speed of information processing. In 2019, new regression-based norms for the English version of the SKT were calculated. This study has two aims: to establish valid cut-offs for distinguishing between no cognitive impairment, mild cognitive impairment (MCI), and dementia (1) and to cross-validate the new norms for detecting MCI and dementia in a community sample of older adults with clinical diagnoses (2). <b>Methods:</b> The validation sample included 143 older adults (mean age = 87.7, SD = 3.55) from the Sydney Memory and Aging Study (MAS Study). Participants were classified as having normal cognition, MCI, or dementia solely based on a consensus diagnosis; in addition, three tests (SKT, Mini-Mental State Examination (MMSE), and Addenbrooke's Cognitive Examination III (ACE-III)) to measure cognitive impairment were applied. Sensitivity and specificity for all three tests, as well as bivariate correlations, were calculated. <b>Results:</b> The sensitivity of the SKT for the differentiation of cognitive impairment (MCI or dementia) from normal cognition was 80.6%. The convergence between the SKT and the consensus diagnoses was 70.3% for all three diagnostic groups. All correlations between the three tests and the consensus diagnosis were significant (<i>p</i> < 0.01). <b>Conclusions:</b> In sum, it can be stated that the SKT is a valid tool for detecting early stages of cognitive impairment, performing very well in discriminating between no cognitive impairment and cognitive impairment (MCI or dementia).
Authors
- Nicole A. Kochan (ORCID: https://orcid.org/0000-0002-8630-6398)
- Mark Stemmler (ORCID: https://orcid.org/0000-0003-4321-1302)
- Henry Brodaty (ORCID: https://orcid.org/0000-0001-9487-6617)
- Katya T. Numbers (ORCID: https://orcid.org/0000-0002-7009-2401)
- Perminder Singh Sachdev (ORCID: https://orcid.org/0000-0002-9595-3220)
- Melina Arnold (ORCID: https://orcid.org/0000-0003-1700-6831)
Institutions
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- UNSW Sydney (AU)
- Prince of Wales Hospital (AU)
Publication Details
- Journal
- Diagnostics
- Published
- 2024-10-02
- DOI
- https://doi.org/10.3390/diagnostics14192199
- Citations
- 2
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- University of New South Wales
- Medical Research Council
- National Health and Medical Research Council