Treatment with brivaracetam has no apparent long‐term effects on body weight in pediatric patients with epilepsy
Brivaracetam is an antiseizure medication (ASM) used to treat seizures in people with epilepsy. Some ASMs can lead to changes in people's appetite and weight. Knowing the effect a drug has on appetite and weight is particularly important in children. We looked at 209 children with epilepsy taking brivaracetam and studied changes in their body weight and body mass index over time. The number of reported side effects related to appetite or weight change was low. There was no apparent long-term effect on their body weight, even when taking their medical history and use of other ASMs into account.
Authors
- Paula Reichel (ORCID: https://orcid.org/0009-0008-2789-7176)
- Sofia Fleyshman
- Florin Floricel (ORCID: https://orcid.org/0009-0008-4982-1092)
- Jan‐Peer Elshoff (ORCID: https://orcid.org/0000-0001-6366-1525)
- Christoph Reichel (ORCID: https://orcid.org/0009-0001-8145-2767)
- Najla Dickson
Institutions
- University Hospital Schleswig-Holstein (DE)
- UCB Pharma (United States) (US)
- UCB Pharma (Germany) (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- Epilepsia Open
- Published
- 2024-10-02
- DOI
- https://doi.org/10.1002/epi4.13045
- Citations
- 1
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- UCB Pharma