Identifying therapeutic targets for primary ovarian insufficiency through integrated genomic analyses
Our study establishes a causal link between specific genes and POI, highlighting FANCE and RAB2A as potential drug targets. These findings provide a foundation for future research and therapeutic development, aiming to improve outcomes for women with POI. Validation in further trials is necessary to confirm these potential targets.
Authors
- Xuyi Liu
- Pengfei Zeng (ORCID: https://orcid.org/0000-0003-2994-9183)
- Zhonglu Huang
- Jun Zhang (ORCID: https://orcid.org/0000-0002-3197-0427)
- Haihong Du
Institutions
- Meizhou City People's Hospital (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2024-10-02
- DOI
- https://doi.org/10.1186/s13048-024-01524-y
- Citations
- 4
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 2.17