Serum TNFα and IL-17A levels may predict increased depressive symptoms: findings from the Shika Study cohort project in Japan
In this cross-sectional study, we found a significant positive correlation between the depressive symptoms and serum TNFα and IL-17A levels of women. In addition, our longitudinal findings suggest the possibility that TNFα and IL-17A could elevate the depressive symptoms of men.
Authors
- Aki Shibata (ORCID: https://orcid.org/0000-0002-8280-869X)
- Jiaye Zhao (ORCID: https://orcid.org/0000-0002-7719-972X)
- Yukari Shimizu (ORCID: https://orcid.org/0000-0003-0670-2671)
- Hirohito Tsuboi
- Atsushi Tajima (ORCID: https://orcid.org/0000-0001-6808-5491)
- Hiroyuki Nakamura (ORCID: https://orcid.org/0000-0002-4461-2098)
- Chie Takazawa (ORCID: https://orcid.org/0009-0003-6712-3371)
- Hiroyuki Sakakibara (ORCID: https://orcid.org/0000-0003-4497-1311)
- Hiromasa Tsujiguchi (ORCID: https://orcid.org/0000-0001-7511-0165)
- Aya Ogawa (ORCID: https://orcid.org/0000-0002-4422-2567)
- Keita Suzuki (ORCID: https://orcid.org/0000-0003-2833-4080)
- Yasuhiro Kambayashi (ORCID: https://orcid.org/0000-0002-0380-0404)
- Sakae Miyagi (ORCID: https://orcid.org/0000-0002-0608-7843)
- Fumihiko Suzuki (ORCID: https://orcid.org/0000-0002-5156-9729)
- Masaharu Nakamura (ORCID: https://orcid.org/0000-0002-1419-2117)
- Takayuki Kannon (ORCID: https://orcid.org/0000-0001-9866-1621)
- Akinori Hara (ORCID: https://orcid.org/0000-0002-0399-1474)
- Tadashi Konoshita (ORCID: https://orcid.org/0000-0001-7104-9758)
- Yuuki Minamida-Urata
Institutions
- Kanazawa University (JP)
- Okayama University of Science (JP)
- University of Shiga Prefecture (JP)
- Ohu University (JP)
- Komatsu University (JP)
- Kanazawa University Hospital (JP)
- Fujita Health University Hospital (JP)
- Tokyo Women's Medical University (JP)
- Kobe University (JP)
Publication Details
- Journal
- BioPsychoSocial Medicine
- Published
- 2024-10-02
- DOI
- https://doi.org/10.1186/s13030-024-00317-5
- Citations
- 4
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.63
Funders
- Ministry of Education, Culture, Sports, Science and Technology