A Simple Model to Study Mosaic Gene Expression in 3D Endothelial Spheroids
In the future, this simple approach to endothelial spheroid formation combined with live-cell imaging could be used to rapidly assess the 3D phenotypes and drug and radiation sensitivities arising from mosaic mutations common to brain vascular malformations.
Authors
- Marcus A. Stoodley
- Fahimeh Faqihi (ORCID: https://orcid.org/0000-0002-1359-4616)
- Lucinda S. McRobb (ORCID: https://orcid.org/0000-0001-5492-1903)
- Vivienne S. Lee
Institutions
- Macquarie University (AU)
Publication Details
- Journal
- Journal of Cardiovascular Development and Disease
- Published
- 2024-10-02
- DOI
- https://doi.org/10.3390/jcdd11100305
- Citations
- 3
- Primary Topic
- Angiogenesis and VEGF in Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- National Health and Medical Research Council