Impact of Chronic Kidney Disease on Outcomes in Non-ST Elevation Myocardial Infarction

Background: Chronic kidney disease (CKD) significantly increases the risk of cardiovascular complications, particularly in patients with non-ST segment elevation myocardial infarction (NSTEMI). However, the effects of revascularization procedures on these patients remain under-explored. Objective: This study evaluates outcomes in CKD patients presenting with NSTEMI, focusing on major adverse cardiovascular events (MACE) and renal function. Methods: A prospective study was conducted at Alexandria University Hospital from December 2022 to June 2023, involving 50 NSTEMI patients, categorized into CKD (Group 1) and non-CKD (Group 2). We analyzed demographic data, revascularization rates, complications during hospitalization and at three months post-discharge, and changes in renal function. Results: CKD patients showed higher rates of renal deterioration and adverse cardiovascular outcomes. Revascularization significantly improved both renal and cardiovascular outcomes for CKD patients, mitigating renal function decline compared to those who did not undergo revascularization. Conclusion: CKD patients with NSTEMI face a greater risk of in-hospital complications, including heart failure and mortality. Nonetheless, revascularization is vital for enhancing cardiovascular and renal outcomes in this high-risk group.