Transmission of multidrug-resistant tuberculosis in Jiangxi, China, and associated risk factors
The high prevalence of multidrug-resistant tuberculosis (MDR-TB) in Jiangxi Province highlights the importance of understanding the genetic background and drug resistance patterns of these strains. This knowledge is crucial for developing effective control methods. Furthermore, in light of the significance of preventing transmission among tuberculosis patients, whole-genome sequencing was utilized to investigate the recent transmission of MDR-TB and identify associated risk factors. The findings revealed that individuals in the farming sector, those who are unemployed, and patients with a history of tuberculosis treatment are at elevated risk. Consequently, targeted public interventions for these at-risk groups are imperative.
Authors
- Jiahuan Zhan (ORCID: https://orcid.org/0000-0001-8965-4673)
- Shengming Yu
- Wei Wang (ORCID: https://orcid.org/0000-0002-5976-9506)
- Kaisen Chen
- Dong Luo (ORCID: https://orcid.org/0000-0002-3411-1134)
- Yan Liang (ORCID: https://orcid.org/0000-0002-6368-6471)
- Qiang Chen (ORCID: https://orcid.org/0009-0009-4215-5901)
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Jiangxi Chest Hospital (CN)
Publication Details
- Journal
- Microbiology Spectrum
- Published
- 2024-10-02
- DOI
- https://doi.org/10.1128/spectrum.03555-23
- Citations
- 4
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.56
Funders
- National Natural Science Foundation of China
- Jiangxi Provincial Department of Science and Technology