Incidence, In-Hospital and Long-Term Mortality, and Sequelae of Epidermal Necrolysis in Adults

The findings of this cohort study suggest that although EN is a rare condition, it is associated with high rates of in-hospital and postdischarge mortality among patients who are older and have comorbid conditions. However, in contrast with in-hospital mortality, postdischarge mortality is not associated with EN initial severity but with acute in-hospital complications (eg, acute kidney injury and sepsis). Future studies are needed to construct models to estimate long-term outcomes and sequelae in patients with EN.

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Publication Details

Journal
JAMA Dermatology
Published
2024-10-02
DOI
https://doi.org/10.1001/jamadermatol.2024.3575
Citations
6
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
2.69
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article

Incidence, In-Hospital and Long-Term Mortality, and Sequelae of Epidermal Necrolysis in Adults

Thomas Bettuzzi, S. Oro, É. Sbidian, Bénédicte Lebrun-Vignes
6 citations
JAMA Dermatology
Drug-Induced Adverse Reactions
2.69
article

Incidence, In-Hospital and Long-Term Mortality, and Sequelae of Epidermal Necrolysis in Adults

Thomas Bettuzzi, S. Oro, É. Sbidian, Bénédicte Lebrun-Vignes
article en
6 citations

Abstract

The findings of this cohort study suggest that although EN is a rare condition, it is associated with high rates of in-hospital and postdischarge mortality among patients who are older and have comorbid conditions. However, in contrast with in-hospital mortality, postdischarge mortality is not associated with EN initial severity but with acute in-hospital complications (eg, acute kidney injury and sepsis). Future studies are needed to construct models to estimate long-term outcomes and sequelae in patients with EN.

JAMA DermatologyVol. 160(12)
Inserm (FR), Université Paris-Est Créteil (FR), Assistance Publique – Hôpitaux de Paris (FR), Epidemiology in dermatology and evaluation of therapeutics
Good health and well-being
Openalex Percentile: Top 10%
Drug-Induced Adverse Reactions
2.69
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