Modification of transvaginal polypropylene mesh with co-axis electrospun nanofibrous membrane to alleviate complications following surgical implantation
The nanofibrous membrane-coated PP mesh effectively reduced the surgical implantation complications by inhibiting the catabolism of collagen in tissues and improving the biocampibility of PP mesh. The incorporation of co-axial fibers composed of polyurethane and gelatin with polypropylene mesh holds promise for the development of enhanced surgical materials for pelvic organ prolapse in clinical applications.
Authors
- Jinghe Lang
- Tao Guo (ORCID: https://orcid.org/0000-0002-6898-9797)
- Xiuqi Wang (ORCID: https://orcid.org/0000-0003-2033-9485)
- Xuechun Hu
- Zhijing Sun (ORCID: https://orcid.org/0000-0001-7187-0431)
- Jian Liu (ORCID: https://orcid.org/0000-0002-8600-3979)
- Haiyan Xu
- Zhe Du (ORCID: https://orcid.org/0000-0003-0311-2916)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2024-10-03
- DOI
- https://doi.org/10.1186/s12951-024-02872-z
- Citations
- 4
- Primary Topic
- Hernia repair and management
- Type
- article
- Field-Weighted Citation Impact
- 2.29
Funders
- National Natural Science Foundation of China
- Capital Foundation of Medical Development