Xiao-Er-Kang-Du capsules regulate autophagy against the influenza B virus (Victoria strain) through the mTOR/ULK1/Beclin1/VPS34 pathway
IBV infection was found to inhibit autophagy, which exacerbated inflammatory damage. XEKD regulates autophagy through the mTOR/ULK1/Beclin1/VPS34 pathway and exerts antiviral effects, thereby laying a foundation for further development of XEKD as a potential therapeutic against IBV infection.
Authors
- Jingjing Li (ORCID: https://orcid.org/0000-0002-0047-3217)
- Jicheng Han
- Haiyang Zhang (ORCID: https://orcid.org/0000-0001-7951-0502)
- Rui Chen (ORCID: https://orcid.org/0000-0002-1587-0362)
- Yan Xiao
- Yan Cao (ORCID: https://orcid.org/0000-0003-3430-6385)
- Liping Sun (ORCID: https://orcid.org/0000-0003-1993-8544)
- Meiwen Dong
- Ruikang Fang
- Guangze Zhu
- Zhongtian Wang (ORCID: https://orcid.org/0000-0003-3417-9865)
- Jing Han (ORCID: https://orcid.org/0000-0003-0048-2241)
Institutions
- Changchun University of Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2024-10-02
- DOI
- https://doi.org/10.1016/j.jep.2024.118872
- Citations
- 1
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- National Natural Science Foundation of China