The LINC00319 binding to STAT3 promotes the cell proliferation, migration, invasion and EMT process in oral squamous cell carcinoma
This study uncovers that LINC00319 promotes OSCC tumorigenesis by directly binding to and activating STAT3 signaling. These findings provide new insights into the regulatory mechanisms of STAT3 by long non-coding RNAs and highlight the potential of LINC00319 as a biomarker and therapeutic target in OSCC.
Authors
- Xiao Jiang (ORCID: https://orcid.org/0000-0001-6893-9370)
- Wenxia Meng (ORCID: https://orcid.org/0000-0003-2471-633X)
- Simin Li (ORCID: https://orcid.org/0000-0003-4011-0282)
- Wenli Gu (ORCID: https://orcid.org/0000-0002-9964-8805)
- Xiaoheng Xu (ORCID: https://orcid.org/0000-0001-8215-8976)
- Xueyi Liang (ORCID: https://orcid.org/0000-0002-7075-4030)
- Yinshen Yang
- Fanping Cheng
Institutions
- Guangdong Province Stomatological Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Archives of Biochemistry and Biophysics
- Published
- 2024-10-02
- DOI
- https://doi.org/10.1016/j.abb.2024.110170
- Citations
- 6
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.71