Identification of SLC22A17 DNA methylation hotspot as a potential biomarker in cutaneous melanoma
The SLC22A17 methDNA hotspot could represent a promising biomarker for CM, highlighting the regulatory role of methDNA on SLC22A17 expression. These results pave the way for the identification of novel epigenetic biomarkers and therapeutic targets for the management of CM patients.
Authors
- Massimo Libra (ORCID: https://orcid.org/0000-0002-7232-7737)
- Alessandro Lavoro (ORCID: https://orcid.org/0000-0001-7844-0354)
- Luca Falzone (ORCID: https://orcid.org/0000-0001-7349-6826)
- James A. McCubrey (ORCID: https://orcid.org/0000-0001-6027-3156)
- Gabriele Madonna (ORCID: https://orcid.org/0000-0001-9395-3190)
- Mariaelena Capone (ORCID: https://orcid.org/0000-0002-1352-2532)
- Giuseppe Gattuso (ORCID: https://orcid.org/0000-0001-5931-2648)
- Rosario Caltabiano (ORCID: https://orcid.org/0000-0001-8591-8010)
- Saverio Candido (ORCID: https://orcid.org/0000-0003-1255-6666)
- G. Conti (ORCID: https://orcid.org/0009-0005-9069-5823)
- Paolo A. Ascierto
Institutions
- East Carolina University (US)
- University of Catania (IT)
- Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-10-02
- DOI
- https://doi.org/10.1186/s12967-024-05622-9
- Citations
- 5
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 1.17